Roxatidine Acetate (hydrochloride)

Roxatidine acetate is a competitive histamine H2 receptor antagonist that upon oral absorption is rapidly converted to its active metabolite roxatidine. By inhibiting the binding of histamine to H2 receptors, roxatidine reduces both intracellular cAMP concentrations and gastric acid secretion by parietal cells.Formal Name: 2-(acetyloxy)-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-acetamide, monohydrochloride. CAS Number: 93793-83-0. Synonyms: HOE 760, TZU-0460. Molecular Formula: C19H28N2O4 . HCl. Formula Weight: 384.9. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 78 mg/ml, Ethanol: 12 mg/ml, Water: 77 mg/ml. lambdamax: 223, 277 nm. SMILES: O=C(COC(C)=O)NCCCOC1=CC=CC(CN2CCCCC2)=C1.Cl. InChi Code: InChI=1S/C19H28N2O4.ClH/c1-16(22)25-15-19(23)20-9-6-12-24-18-8-5-7-17(13-18)14-21-10-3-2-4-11-21,/h5,7-8,13H,2-4,6,9-12,14-15H2,1H3,(H,20,23),1H. InChi Key: FEWCTJHCXOHWNL-UHFFFAOYSA-N.