Rivaroxaban-d4

Description: Rivaroxaban D4 is a deuterium labeled Rivaroxaban. Rivaroxaban is a highly potent,selective and direct inhibitor of Factor Xa (FXa)(IC50:0.7 nM, Ki:0.4 nM). Smiles: [2H]c1c([2H])c(c([2H])c([2H])c1N1C[C@H](CNC(=O)c2ccc(Cl)s2)OC1=O)N1CCOCC1=O. References: Roehrig S, et al. Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor. J Med Chem. 2005 Sep 22,48(19)