Rifampicin-d3

Rifampicin-d3
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay27848-500 500 µg -

6 - 10 Werktage*

406,00 €
 
Rifampicin-d3 is intended for use as an internal standard for the quantification of rifampicin... mehr
Produktinformationen "Rifampicin-d3"
Rifampicin-d3 is intended for use as an internal standard for the quantification of rifampicin (Cay-14423) by GC- or LC-MS. Rifampicin is a rifamycin antibiotic and inhibitor of bacterial RNA polymerase (IC50 = 0.01 µg/ml for the E. coli enzyme). It inhibits the growth of M. tuberculosis H37Rv in mouse peritoneal macrophages (MIC = 0.8 µg/ml) as well as clinical isolates of various species of Staphylococcus, Streptococcus, Haemophilus, and Neisseria (MICs = 0.009-1.4 µg/ml). Rifampicin increases survival in a mouse model of tuberculosis infection. It is also an agonist of the human pregnane X receptor (PXR, EC50 = ~2 µM). Formulations containing rifampicin have been used in the treatment of tuberculosis and meningococcal carriers.Formal Name: 3-[[(4-(methyl-d3)-1-piperazinyl)imino]methyl]-rifamycin. CAS Number: 1262052-36-7. Synonyms: Rifampin-d3. Molecular Formula: C43H55D3N4O12. Formula Weight: 826.0. Purity: >99% deuterated forms (d1-d3). Formulation: (Request formulation change), A solid. Solubility: Chloroform: slightly soluble, Methanol: slightly soluble. SMILES: OC1=C2C(C(O)=C(C)C(O[C@]3(C)O/C=C/[C@H](OC)[C@H](C)[C@]([C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)/C=C/C=C(C)/C(N4)=O)(OC(C)=O)[H])=C2C3=O)=C(O)C4=C1/C=N/N5CCN(C([2H])([2H])[2H])CC5. InChi Code: InChI=1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13+,44-20+/t21-,23-,24+,25+,29-,34-,35+,39+,43-/m0/s1/i9D3. InChi Key: JQXXHWHPUNPDRT-RBOQPHAKSA-N.
Schlagworte: Rifampin-d3, 3-[[(4-(methyl-d3)-1-piperazinyl)imino]methyl]-rifamycin
Hersteller: Cayman Chemical
Hersteller-Nr: 27848

Eigenschaften

Anwendung: GC-MS, LC-MS, Internal standard, Quantification
MW: 826 D
Formel: C43H55D3N4O12
Reinheit: >99% deuterated forms (d1-d3)
Format: Solid

Datenbank Information

CAS : 1262052-36-7| Passende Produkte
KEGG ID : K01980 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: -20°C)
Signalwort: Warning
GHS-Piktogramme:
H-Sätze: H302, H315, H319, H335
P-Sätze: P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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