Ribocil

Description: Ribocil is a highly selective chemical modulator of bacterial riboflavin riboswitches, strongly inhibiting GFP expression with a 50% effective concentration (EC50: 0.3 µM). Target: Antibacterial. Smiles: CNc1ncc(CN2CCCC(C2)c2nc(=O)cc([nH]2)-c2cccs2)cn1. References: Howe JA, et al. Selective small-molecule inhibition of an RNA structural element. Nature. 2015 Oct 29,526(7575):672-7.