Rhod-2 AM

Rhod-2 AM is an acetoxymethyl (AM) ester of the red fluorescent calcium indicator rhod-2. The AM group facilitates cellular uptake and is removed by cytoplasmic esterases, resulting in intracellular accumulation of rhod-2. Rhod-2 AM selectively accumulates within mitochondria and, as a result, is commonly used to monitor calcium changes within this organelle. Excitation and emission maxima are 557 and 581 nm, respectively.Formal Name: 9-[4-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-3-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]phenoxy]ethoxy]phenyl]-3,6-bis(dimethylamino)-xanthylium, monobromide. CAS Number: 145037-81-6. Synonyms: Rhod-2 Acetoxymethyl ester. Molecular Formula: C52H59N4O19 . Br. Formula Weight: 1124.0. Purity: >93%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble. lambdamax: 215, 255, 549 nm. SMILES: O=C(CN(C1=C(OCCOC2=C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C=CC(C)=C2)C=C(C3=C4C=CC(N(C)C)=CC4=[O+]C5=CC(N(C)C)=CC=C35)C=C1)CC(OCOC(C)=O)=O)OCOC(C)=O.[Br-]. InChi Code: InChI=1S/C52H59N4O19.BrH/c1-32-10-16-42(55(24-48(61)71-28-67-33(2)57)25-49(62)72-29-68-34(3)58)46(20-32)65-18-19-66-47-21-37(11-17-43(47)56(26-50(63)73-30-69-35(4)59)27-51(64)74-31-70-36(5)60)52-40-14-12-38(53(6)7)22-44(40)75-45-23-39(54(8)9)13-15-41. InChi Key: RWXWZOWDWYQKBK-UHFFFAOYSA-M.