Quinolactacin A

Description: Quinolactactin A is a quinolone fungal metabolite originally isolated from Penicillium. It inhibits TNF production induced by LPS in murine peritoneal macrophages (IC50 = 12.2 µg/ml). It is not active against a variety of bacteria, fungi, and yeasts. Quinolactacin A is a mixture of quinolactacin A1 and A2. Target: Others. Smiles: CC[C@@H](C)[C@@H]1NC(=O)c2c1n(C)c1ccccc1c2=O