Quinolactacin A

Quinolactactin A is a quinolone fungal metabolite originally isolated from Penicillium. It inhibits TNF production induced by LPS in murine peritoneal macrophages (IC50 = 12.2 µg/ml). It is not active against a variety of bacteria, fungi, and yeasts. Quinolactacin A is a mixture of quinolactacin A1 and A2.Formal Name: (3S)-2,3-dihydro-4-methyl-3-(1-methylpropyl)-1H-pyrrolo[3,4-b]quinoline-1,9(4H)-dione. CAS Number: 319917-25-4. Molecular Formula: C16H18N2O2. Formula Weight: 270.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble, Ethanol: 1 mg/ml, Methanol: Soluble. SMILES: O=C1C2=C([C@@](C(CC)C)([H])NC2=O)N(C)C3=C1C=CC=C3. InChi Code: InChI=1S/C16H18N2O2/c1-4-9(2)13-14-12(16(20)17-13)15(19)10-7-5-6-8-11(10)18(14)3/h5-9,13H,4H2,1-3H3,(H,17,20)/t9?,13-/m0/s1. InChi Key: FLHQAMWKNPOTDV-NCWAPJAISA-N. Origin: Fungus/Penicillium citrinum.