Quercetin-d3 (hydrate)

Quercetin-d3(hydrate) is intended for use as an internal standard for the quantification of quercetin (Cay-10005169) by GC- or LC-MS. Quercetin is an abundant flavonoid that has been isolated from a variety of plants and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. Quercetin (5-100 mg/kg) reduces autophagy, decreases the levels of reactive oxygen species (ROS) and malondialdehyde (MDA) content, and increases total antioxidant capacity in the kidney in a mouse model of cadmium-induced autophagy. It reduces tumor growth, induces apoptosis, and halts the cell cycle at the G1 phase in an HL60 mouse xenograft model when administered at a dose of 120 mg/kg every four days. Quercetin (30 µM) also inhibits histamine release from antigen-stimulated RBL-2H3 cells and decreases the expression of TNF-alpha, IL-1beta, IL-6, and IL-8 induced by PMACI in HMC-1 cells.Formal Name: 2-(4,5-dihydroxyphenyl-2,3,6-d3)-3,5,7-trihydroxy-4H-1-benzopyran-4-one, hydrate. Molecular Formula: C15H7D3O7 . XH2O. Formula Weight: 305.3. Purity: >99% deuterated forms (d1-d3). Formulation: (Request formulation change), A solid. Solubility: DMSO: slightly soluble, Methanol: slightly soluble. SMILES: OC1=CC(O)=C(C(C(O)=C(C2=C([2H])C([2H])=C(O)C(O)=C2[2H])O3)=O)C3=C1.O. InChi Code: InChI=1S/C15H10O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6,/h1-5,16-19,21H,1H2/i1D,2D,3D,. InChi Key: OKXFBEYCJRMINR-KADUPEOVSA-N. Origin: Synthetic.