Procyanidin B2

Description: Procyanidin B2 (Proanthocyanidin B2) has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression of AP-1 pathway. Target: NOD, Reactive Oxygen Species. Smiles: O[C@@H]1Cc2c(O)cc(O)c([C@@H]3[C@@H](O)[C@H](Oc4cc(O)cc(O)c34)c3ccc(O)c(O)c3)c2O[C@@H]1c1ccc(O)c(O)c1. References: Sakano K , Mizutani M , Murata M , et al. Procyanidin B2 has anti- and pro-oxidant effects on metal-mediated DNA damage[J]. Free Radical Biology & Medicine, 2005, 39(8):1041-1049.