Potassium oxonate

Description: Potassium oxonate (Potassium azaorotate) is a uricase inhibitor that prevents metabolism and excretion of uric acid and induces embryotoxicity and nephrotoxicity in rats. Target: Others. Smiles: [K+].[O-]C(=O)c1nc(=O)[nH]c(=O)[nH]1. References: Yoshisue K, Masuda H, Matsushima E,et al.Tissue distribution and biotransformation of potassium oxonate after oral administration of a novel antitumor agent (drug combination of tegafur, 5-chloro-2,4-dihydroxypyridine, and potassium oxonate) to rats[J].Drug Metab Dispos. 2000 Oct,28(10):1162-7.