PKC-9

PKC-9 is an inhibitor of PKCzeta that is 8,000-, 20,671-, 711-, 918-, 1,895-, 12,424-, 10-, and 1,218-fold selective for PKCzeta over PKCalpha, PKCbetaII, PKCgamma, PKCdelta, PKCepsilon, PKCeta, PKCiota, and PKCtheta, respectively. It also inhibits 27 additional kinases in a panel of 37 kinases when used at a concentration of 10 µM.Formal Name: 4-[3-[7-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl]-benzenamine. CAS Number: 1132609-87-0. Molecular Formula: C25H25N7. Formula Weight: 423.5. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble. SMILES: NC1=CC=C(C2=CC(NN=C3C4=NC(C=CC=C5N6CCN(C)CC6)=C5N4)=C3C=C2)C=C1. InChi Code: InChI=1S/C25H25N7/c1-31-11-13-32(14-12-31)22-4-2-3-20-24(22)28-25(27-20)23-19-10-7-17(15-21(19)29-30-23)16-5-8-18(26)9-6-16/h2-10,15H,11-14,26H2,1H3,(H,27,28)(H,29,30). InChi Key: LPSCCOBGZSKECZ-UHFFFAOYSA-N.