Pizotifen (malate)

Pizotifen is a triptan with high affinity for serotonin (5-HT) and dopamine receptors (Kis = 7.94 and 2.4 nM for 5-HT2C and D2, respectively). It is used for the prophylaxis of migraine headaches.Formal Name: 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine, 2-hydroxy-butanedioic acid. CAS Number: 5189-11-7. Molecular Formula: C19H21NS . C4H6O5. Formula Weight: 429.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMF:PBS (pH 7.2) (1:8): 0.11 mg/ml, DMSO: 15 mg/ml, Ethanol: 0.5 mg/ml. SMILES: CN(CC/1)CCC1=C2C3=C(C=CC=C3)CCC4=C/2C=CS4.OC(C(O)=O)CC(O)=O. InChi Code: InChI=1S/C19H21NS.C4H6O5/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18,5-2(4(8)9)1-3(6)7/h2-5,10,13H,6-9,11-12H2,1H3,2,5H,1H2,(H,6,7)(H,8,9). InChi Key: IWAWCPZVTXCFKD-UHFFFAOYSA-N.