Pitavastatin lactone

Description: Pitavastatin lactone is the major metabolite of Pitavastatin in humans.Pitavastatin is a competitive inhibitor of HMG-CoA reductase. Target: HMG-CoA Reductase, Others. Smiles: C(=C/[C@@H]1C[C@@H](O)CC(=O)O1)\C2=C(C3=C(N=C2C4CC4)C=CC=C3)C5=CC=C(F)C=C5. References: Fujino H, et al. Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: human UDP-glucuronosyltransferase enzymes involved in lactonization. Xenobiotica. 2003 Jan,33(1):27-41.