Pipotiazine

Description: Pipotiazine has less sedating and a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics among the different phenothiazine derivatives. However, it produces a high incidence of extra pyramidal reactions. It is used for the maintenance treatment of chronic non-agitated schizophrenic patients. Target: Others. Smiles: C(CCN1CCC(CCO)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(S(N(C)C)(=O)=O)C3. References: Haddad P, Taylor M, Patel MX, Taylor D. Guidance on switching away from Piportil Depot(R) (pipotiazine palmitate) injection. Br J Psychiatry. 2015 Jun,206(6):521. doi: 10.1192/bjp.206.6.521. PubMed PMID: 26034183.