Picaridin

Picaridin is an insect repellent. It inhibits A. aegypti odorant receptor 2 (AaOR2) or AaOR8 in the presence of their odorant activators, indole and octenol, respectively, expressed in Xenopus oocytes (IC50s = 1,452 and 1,911 µM, respectively). Picaridin reduces the number of entries into a food chamber by female D. melanogaster in an olfactory-based choice assay. It acts synergistically with the non-pyrethroid insecticide pyrimiphos methyl to increase mortality of A. gambiae and reduce blood feeding when used at a concentration of 10 g/m2 on nets surrounding guinea pig cages. Formulations containing picaridin have been used as insect repellents against flies, mosquitoes, chiggers, ticks, and fleas.Formal Name: 2-(2-hydroxyethyl)-1-piperidinecarboxylic acid, 1-methylpropyl ester. CAS Number: 119515-38-7. Synonyms: Icaridin, KBR 3023. Molecular Formula: C12H23NO3. Formula Weight: 229.3. Purity: >95%. Formulation: (Request formulation change), A neat oil. Solubility: DMF: 30 mg/ml, DMSO: 25 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 2 mg/ml. SMILES: O=C(OC(C)CC)N1C(CCO)CCCC1. InChi Code: InChI=1S/C12H23NO3/c1-3-10(2)16-12(15)13-8-5-4-6-11(13)7-9-14/h10-11,14H,3-9H2,1-2H3. InChi Key: QLHULAHOXSSASE-UHFFFAOYSA-N.