PF-06840003

Description: PF-06840003 (EOS200271) is a specific and orally active IDO-1 inhibitor. Target: IDO, Indoleamine 2,3-Dioxygenase (IDO). Smiles: Fc1ccc2[nH]cc(C3CC(=O)NC3=O)c2c1. References: Tumang J, et al. PF-06840003: a highly selective IDO-1 inhibitor that shows good in vivo efficacy in combination with immune checkpoint inhibitors. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research, 2016 Apr 16-20, New Orleans, LA. Philadelphia (PA): AACR, Cancer Res 2016,76(14 Suppl):Abstract nr4863.