Perfluorotridecanoic Acid

Perfluorotridecanoic acid (PFTrDA) is a perfluoroalkyl substance (PFAS). Embryo-larval exposure of PFTrDA induces yolk sac edema and increases mRNA expression of thyroid hormone synthesis genes, including tshbeta, in zebrafish when used at concentrations of 0.1 and 0.3 mg/L, respectively. PFTrDA (10 mg/kg) decreases serum testosterone and luteinizing hormone levels, testis palmitic acid (Cay-10006627), linoleic acid (Cay-90150, Cay-90150.1, Cay-21909), and oleic acid (Cay-90260, Cay-24659) levels, and the number of Leydig cells in rats in late puberty. Maternal plasma levels of PFTrDA during gestation are positively associated with the development of eczema in female, but not male, infants, and liver levels of PFTrDA are higher in cancerous human livers compared with non-cancerous human livers. It has been found in marine mammals.Formal Name: 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13,13-pentacosafluoro-tridecanoic acid. CAS Number: 72629-94-8. Synonyms: PFTrDA. Molecular Formula: C13HF25O2. Formula Weight: 664.1. Purity: >80%. Formulation: (Request formulation change), A solid. Solubility: Ethanol: Slightly soluble. SMILES: O=C(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(C(F)(F)F)F)F)F)F)F)F)F)F)F)F)F)O. InChi Code: InChI=1S/C13HF25O2/c14-2(15,1(39)40)3(16,17)4(18,19)5(20,21)6(22,23)7(24,25)8(26,27)9(28,29)10(30,31)11(32,33)12(34,35)13(36,37)38/h(H,39,40). InChi Key: LVDGGZAZAYHXEY-UHFFFAOYSA-N.