PC945

Description: PC945 (Opelconazole) is a potent broad-spectrum antifungal compound with inhibitory effect on fumonisinol 14alpha-demethylase (CYP51A/CYP51B), which can be used in the study of fungal infections of the lungs. Target: Others. Smiles: Cc1cc(ccc1OC[C@@H]1CO[C@](Cn2cncn2)(C1)c1ccc(F)cc1F)N1CCN(CC1)c1ccc(cc1)C(=O)Nc1ccc(F)cc1. References: Colley T, et al. Antifungal synergy of a topical triazole, PC945, with a systemic triazole against respiratory Aspergillus fumigatus infection. Sci Rep. 2019 Jul 1,9(1):9482.