PBFI AM

PBFI AM is a cell-permeable, potassium-sensitive fluorophore used to measure potassium changes in cells and intracellular compartments. As PBFI AM enters cells, it is hydrolyzed by intracellular esterases to produce PBFI. The affinity of PBFI for potassium is sodium-dependent (Kd = 44 and 5.1 mM with or without sodium, respectively). Absorption and emission maxima are 336 and 480-557 nm, respectively.Formal Name: 4,4'-[1,4,10,13-tetraoxa-7,16-diazacyclooctadecane-7,16-diylbis(5-methoxy-6,2-benzofurandiyl)]bis-1,3-benzenedicarboxylic acid, tetrakis[(acetyloxy)methyl] ester. CAS Number: 124549-23-1. Synonyms: Potassium-binding Benzofuran Isophthalate Acetoxymethyl ester. Molecular Formula: C58H62N2O24. Formula Weight: 1171.1. Purity: >95%. Emission: 480-557 nm. Excitation: 336 nm. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble, Methanol: Soluble. SMILES: COC1=CC2=C(OC(C3=C(C(OCOC(C)=O)=O)C=C(C(OCOC(C)=O)=O)C=C3)=C2)C=C1N4CCOCCOCCN(C5=CC(OC(C6=C(C(OCOC(C)=O)=O)C=C(C(OCOC(C)=O)=O)C=C6)=C7)=C7C=C5OC)CCOCCOCC4. InChi Code: InChI=1S/C58H62N2O24/c1-35(61)75-31-79-55(65)39-7-9-43(45(23-39)57(67)81-33-77-37(3)63)51-25-41-27-53(69-5)47(29-49(41)83-51)59-11-15-71-19-21-73-17-13-60(14-18-74-22-20-72-16-12-59)48-30-50-42(28-54(48)70-6)26-52(84-50)44-10-8-40(56(66)80-32-76-36(2. InChi Key: AUKRBWNSOWVABU-UHFFFAOYSA-N.