PAF C-16 Carboxylic Acid

PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the "remodeling" and 'de novo' pathways. It is a potent mediator of neutrophil migration and the production of reactive oxygen species and IL-6. Pathological processes involving PAF include necrotizing enterocolitis, inflammation, asthma, and allergy. PAF C-16 Carboxylic acid is modified with a carboxylic acid group terminating the C-16 alkyl chain. This provides a convenient site for chemical crosslinking.Formal Name: (R)-7-(acetyloxy)-24-carboxy-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphatetracosan-1-aminium, inner salt, 4-oxide. CAS Number: 129879-41-0. Synonyms: CPAGP, Platelet-activating Factor C-16 Carboxylic Acid. Molecular Formula: C26H52NO9P. Formula Weight: 553.7. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 1 mg/ml, DMSO: 15 mg/ml, Ethanol: 25 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: C[N+](C)(C)CCOP([O-])(OC[C@H](OC(C)=O)COCCCCCCCCCCCCCCCC(O)=O)=O. InChi Code: InChI=1S/C26H52NO9P/c1-24(28)36-25(23-35-37(31,32)34-21-19-27(2,3)4)22-33-20-17-15-13-11-9-7-5-6-8-10-12-14-16-18-26(29)30/h25H,5-23H2,1-4H3,(H-,29,30,31,32)/t25-/m1/s1. InChi Key: PKDXOBRCEXMRQQ-RUZDIDTESA-N.