Paeoniflorin

Paeoniflorin is a monoterpene glycoside first isolated from the roots of peony. It has diverse cellular actions, including modulating NMDA and TRPV1 receptors. Paeoniflorin is reported to inhibit testosterone synthesis and stimulate aromatase activity. It also reduces inflammatory signaling by inhibiting p38 MAP kinase and blocks pancreatic cancer cell apoptosis by suppressing MMP-9 and ERK signaling. Presumably through some of these actions, paeoniflorin has analgesic and anti-inflammatory actions in mice.Formal Name: (1aR,2S,3aR,5R,5aR,5bS)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl beta-D-glucopyranoside. CAS Number: 23180-57-6. Synonyms: NSC 178886. Molecular Formula: C23H28O11. Formula Weight: 480.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/mL, DMSO: 30 mg/mL, Ethanol: 30 mg/mL, PBS (pH 7.2): 10 mg/mL. lambdamax: 230, 274 nm. SMILES: [H][C@]12O[C@@](C)(C3)[C@](C4)(O[C@@]5([H])[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O5)[C@@]1(COC(C6=CC=CC=C6)=O)[C@]4([H])[C@]3(O)O2. InChi Code: InChI=1S/C23H28O11/c1-20-9-22(29)13-7-23(20,32-18-16(27)15(26)14(25)12(8-24)31-18)21(13,19(33-20)34-22)10-30-17(28)11-5-3-2-4-6-11/h2-6,12-16,18-19,24-27,29H,7-10H2,1H3/t12-,13-,14-,15+,16-,18+,19-,20+,21+,22-,23+/m1/s1. InChi Key: YKRGDOXKVOZESV-WRJNSLSBSA-N.