Oxytetracycline

Oxytetracycline is a broad-spectrum tetracycline antibiotic that inhibits protein synthesis in both Gram-positive and Gram-negative bacteria. The features of its biosynthesis often serve as a representative example for understanding the synthesis of other type II polyketides. Oxytetracycline is also used to examine the acquisition of oxytetracycline-resistance genes, which are associated with the development of antibiotic resistance.Formal Name: (4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide. CAS Number: 79-57-2. Synonyms: NSC 9169, Terramycin. Molecular Formula: C22H24N2O9. Formula Weight: 460.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 0.3 mg/ml, DMSO: 3 mg/ml, DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml. lambdamax: 220, 265, 360 nm. SMILES: O=C1C2=C(O)C=CC=C2[C@](O)(C)[C@]3([H])C1=C(O)[C@@](C(C(C(N)=O)=C(O)[C@H]4N(C)C)=O)(O)[C@@]4([H])[C@H]3O. InChi Code: InChI=1S/C22H24N2O9/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31)/t12-,13-,14+,17+,21-,22+/m1/s1. InChi Key: IWVCMVBTMGNXQD-PXOLEDIWSA-N.