Oxaliplatin

White to off-white powder. Soluble in DMSO or water. Slightly soluble in methanol. Insoluble in ethanol. Potent platinum-based antineoplastic agent with wide spectrum anticancer activity, Anticancer compound. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death, Shows antitumor activity in cisplatin resistant cell lines, Shows better biochemical, pharmacological and cytotoxic properties than cisplatin (Prod. No. AG-CR1-3590) and carboplatin (Prod. No. AG-CR1-3591), Apoptosis inducer, Targets other proteins and enzymes, Anticancer activity and antitumor specificity depends on selective uptake through human organic cation transporters 1 (OCT1) and OCT2, Neurotoxic profile depends on organic cation transporter 2 (OCT2) uptake.