Oseltamivir (phosphate)

Oseltamivir is an antiviral prodrug targeted against the influenza viruses. Once hydrolyzed in the liver to its active metabolite, oseltamivir acid (Cay-15779), it can competitively inhibit viral neuraminidase (IC50s = 0.1-4.9 nM for influenza neuraminidases A and B), blocking the release of new viral particles from a host cell.Formal Name: 4R-(acetylamino)-5S-amino-3R-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid, ethyl ester, monophosphate. CAS Number: 204255-11-8. Synonyms: GS-4104, Ro 64-0796/002. Molecular Formula: C16H28N2O4 . H3PO4. Formula Weight: 410.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 0.5 mg/ml, DMSO: 10 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: N[C@@H]1[C@@H](NC(C)=O)[C@H](OC(CC)CC)C=C(C(OCC)=O)C1.O=P(O)(O)O. InChi Code: InChI=1S/C16H28N2O4.H3O4P/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(17)15(14)18-10(4)19,1-5(2,3)4/h9,12-15H,5-8,17H2,1-4H3,(H,18,19),(H3,1,2,3,4)/t13-,14+,15+,/m0./s1. InChi Key: PGZUMBJQJWIWGJ-ONAKXNSWSA-N.