Omeprazole-d3

Omeprazole-d3
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay22087-500 500 µg -

6 - 10 Werktage*

156,00 €
Cay22087-1 1 mg -

6 - 10 Werktage*

232,00 €
Cay22087-5 5 mg -

6 - 10 Werktage*

691,00 €
 
Omeprazole-d3 is intended for use as an internal standard for the quantification of omeprazole... mehr
Produktinformationen "Omeprazole-d3"
Omeprazole-d3 is intended for use as an internal standard for the quantification of omeprazole (Cay-14880) by GC- or LC-MS. Omeprazole is an inhibitor of gastric H+/K+ ATPase (IC50 = 1.1 µM for the pig ATPase). It is a racemic mixture of esomeprazole (Cay-17303) and (R)-omeprazole (Cay-18874). Omeprazole (100 µM) decreases zymosan-induced oxygen free radical production in isolated human neutrophils. It is active against 17 strains of H. pylori (MIC50s = 12.5-50 µg/ml). It decreases histamine-induced acid secretion in dogs (ED50 = 0.35 µmol/kg). Formulations containing omeprazole have been used in the treatment of duodenal and gastric ulcers, gastroesophageal reflux disease, and erosive esophagitis.Formal Name: 6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole-4,5,7-d3. CAS Number: 934293-92-2. Synonyms: OMEP-d3, OMP-d3, OMZ-d3. Molecular Formula: C17H16D3N3O3S. Formula Weight: 348.4. Purity: >99% deuterated forms (d1-d3), =1% d0. Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 5 mg/ml. SMILES: COC1=C([2H])C([2H])=C2C(N=C(S(CC3=C(C)C(OC)=C(C)C=N3)=O)N2)=C1[2H]. InChi Code: InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)/i5D,6D,7D. InChi Key: SUBDBMMJDZJVOS-CRSPMMAGSA-N.
Schlagworte: OMEP-d3, OMP-d3, OMZ-d3, 6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole-4,5,7-d3
Hersteller: Cayman Chemical
Hersteller-Nr: 22087

Eigenschaften

Anwendung: GC-MS, LC-MS, internal standard
MW: 348.4 D
Formel: C17H16D3N3O3S
Reinheit: >99% deuterated forms (d1-d3), <=1% d0
Format: Solid

Datenbank Information

CAS : 934293-92-2| Passende Produkte
KEGG ID : K01543 | Passende Produkte

Handhabung & Sicherheit

Lagerung: +20°C
Versand: +20°C (International: +20°C)
Signalwort: Warning
GHS-Piktogramme:
H-Sätze: H315, H319, H335
P-Sätze: P261, P264, P271, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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