Omecamtiv Mecarbil

Omecamtiv mecarbil is a cardiac myosin ATPase activator with a 40% activation concentration (AC40) value of 0.58 µM for the bovine enzyme. It increases fractional shortening in rats in a dose-dependent manner.Formal Name: 4-[[2-fluoro-3-[[[(6-methyl-3-pyridinyl)amino]carbonyl]amino]phenyl]methyl]-1-piperazinecarboxylic acid, methyl ester. CAS Number: 873697-71-3. Synonyms: CK-1827452. Molecular Formula: C20H24FN5O3. Formula Weight: 401.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMF:PBS(pH7.2) (1:2): 0.33 mg/ml, DMSO: 10 mg/ml, Ethanol: 5 mg/ml. lambdamax: 256 nm. SMILES: COC(N1CCN(CC2=CC=CC(NC(NC3=CC=C(C)N=C3)=O)=C2F)CC1)=O. InChi Code: InChI=1S/C20H24FN5O3/c1-14-6-7-16(12-22-14)23-19(27)24-17-5-3-4-15(18(17)21)13-25-8-10-26(11-9-25)20(28)29-2/h3-7,12H,8-11,13H2,1-2H3,(H2,23,24,27). InChi Key: RFUBTTPMWSKEIW-UHFFFAOYSA-N.