Oleoyl-L-carnitine chloride

Description: Oleoyl-L-carnitine, a long-chain acylcarnitine, acts as a selective inhibitor of glycine transporter 2 (GlyT2, IC50 = 340 nM) while demonstrating significantly lesser affinity for GlyT1 (IC50 = >10,000 nM). Elevated plasma levels of this compound have been observed in patients suffering from chronic kidney disease or end-stage renal disease undergoing initial hemodialysis, correlating with an increased risk of cardiovascular mortality. Target: Others. Smiles: OC(C[C@H](C[N+](C)(C)C)OC(CCCCCCC/C=C\CCCCCCCC)=O)=O.[Cl-]