Octenidine (hydrochloride)

Octenidine is an antimicrobial agent. It is active against a variety of bacteria, including methicillin-sensitive and -resistant S. aureus, vancomycin-resistant Enterococcus, E. faecalis, and S. pneumoniae (MICs = 1-32 mg/L), and the fungus C. albicans (MIC = 1 mg/L). Octenidine (2 mM) reduces methicillin- or vancomycin-resistant S. aureus biofilm formation. Topical application of octenidine (1%) reduces dental plaque accumulation in cynomolgus monkeys fed a high-sucrose diet.Formal Name: N,N'-(1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-1-octanamine, dihydrochloride. CAS Number: 70775-75-6. Synonyms: WIN 41,464-2. Molecular Formula: C36H62N4 . 2HCl. Formula Weight: 623.8. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 10 mg/ml, DMSO: 5 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:7): 0.12 mg/ml. lambdamax: 214, 284 nm. SMILES: CCCCCCCC/N=C(C=C1)/C=CN1CCCCCCCCCCN(C=C/2)C=CC2=N/CCCCCCCC.Cl.Cl. InChi Code: InChI=1S/C36H62N4.2ClH/c1-3-5-7-9-15-19-27-37-35-23-31-39(32-24-35)29-21-17-13-11-12-14-18-22-30-40-33-25-36(26-34-40)38-28-20-16-10-8-6-4-2,,/h23-26,31-34H,3-22,27-30H2,1-2H3,2*1H. InChi Key: SMGTYJPMKXNQFY-UHFFFAOYSA-N.