Ochratoxin B

Ochratoxin B (OTB) is a mycotoxin that has been found in Aspergillus and is a non-chlorinated derivative of OTA (Cay-11439). Unlike OTA, OTB is not genotoxic to HepG2 cells but does inhibit cell division when used at concentrations ranging from 1 to 25 µg/ml. It induces mortality (LC50 = 700 nM) and craniofacial malformations (EC50 = 200 nM) in Xenopus embryos. OTB has been found in poultry feed.Formal Name: N-[[(3R)-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine. CAS Number: 4825-86-9. Synonyms: OTB. Molecular Formula: C20H19NO6. Formula Weight: 369.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 15 mg/ml, Ethanol: 50 mg/ml, Ethanol:PBS (pH 7.2) (1:1): 0.50 mg/ml. lambdamax: 218, 319 nm. SMILES: O=C1O[C@@H](C)CC2=C1C(O)=C(C(N[C@H](C(O)=O)CC3=CC=CC=C3)=O)C=C2. InChi Code: InChI=1S/C20H19NO6/c1-11-9-13-7-8-14(17(22)16(13)20(26)27-11)18(23)21-15(19(24)25)10-12-5-3-2-4-6-12/h2-8,11,15,22H,9-10H2,1H3,(H,21,23)(H,24,25)/t11-,15-/m0/s1. InChi Key: DAEYIVCTQUFNTM-NHYWBVRUSA-N.