Nordihydroguaiaretic acid

Description: Nordihydroguaiaretic acid (NDGA) (NDGA) is a phenolic antioxidant found in the leaves and twigs of the evergreen desert shrub, Larrea tridentata (Sesse and Moc. ex DC) Coville (creosote bush). It is a recognized inhibitor of lipoxygenase (LOX) and has antioxidant and free radical scavenging properties. Target: Autophagy, Lipoxygenase, Antioxidant, Ferroptosis. Smiles: CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1. References: Lu F, et al. Virtual Screening for Potential Allosteric Inhibitors of Cyclin-Dependent Kinase 2 from Traditional Chinese Medicine. Molecules. 2016 Sep 21,21(9). pii: E1259.