nNOS Inhibitor I

nNOS inhibitor I is a cell-permeable, selective inhibitor of nNOS (Ki = 120 nM). It displays >2,500-fold and 320-fold selectivity over eNOS and iNOS, respectively. It has been used in a rabbit model for cerebral palsy to prevent hypoxia-ischemia-induced death and to reduce the number of newborn kits exhibiting signs of cerebral palsy.Formal Name: N-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-N'-nitro-guanidine, tris(2,2,2-trifluoroacetate). CAS Number: 357965-99-2. Synonyms: Neuronal Nitric Oxide Synthase, NOS I, ncNOS. Molecular Formula: C8H21N7O2 . 3CF3COOH. Formula Weight: 589.4. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Water: 50 mg/ml. lambdamax: 269 nm. SMILES: N=C(NCCC[C@H](N)CNCCN)N[N+]([O-])=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O. InChi Code: InChI=1S/C8H21N7O2.3C2HF3O2/c9-3-5-12-6-7(10)2-1-4-13-8(11)14-15(16)17,3*3-2(4,5)1(6)7/h7,12H,1-6,9-10H2,(H3,11,13,14),3*(H,6,7)/t7-,,,/m0.../s1. InChi Key: NYWNMNBIORWOSQ-QTPLPEIMSA-N.