Nitrofurantoin

Description: Nitrofurantoin (Furadantine), an antibiotic, inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoin is used prophylactically as a urinary anti-infective agent against most gram-positive and gram-negative organisms and for long-term suppression of infections. Target: Antibacterial, Antibiotic. Smiles: N(=CC=1OC(N(=O)=O)=CC1)N2CC(=O)NC2=O. References: Yeo SJ, et al. In Vitro and in Vivo Effects of Nitrofurantoin on Experimental Toxoplasmosis. Korean J Parasitol. 2016 Apr,54(2):155-61.