Nintedanib

Artikelnummer	Größe	Lieferzeit	Preis
TGM-T1777-5mg	5 mg	7 - 10 Werktage*	40,00 €
TGM-T1777-1mL	1 ml	7 - 10 Werktage*	52,00 €
TGM-T1777-10mg	10 mg	7 - 10 Werktage*	54,00 €
TGM-T1777-50mg	50 mg	7 - 10 Werktage*	64,00 €
TGM-T1777-100mg	100 mg	7 - 10 Werktage*	93,00 €
TGM-T1777-200mg	200 mg	7 - 10 Werktage*	147,00 €

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Description: Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1,... mehr

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Produktinformationen "Nintedanib"

Description: Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108 nM), PDGFRalpha, and PDGFRbeta (IC50=59/65 nM). Nintedanib has antitumor activity and inhibits tumor growth by inhibiting angiogenesis. Target: FGFR, VEGFR, FLT, PDGFR, Src. Smiles: COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)N(CCOC(=O)c3ccc4\C(=C(\Nc5ccc(cc5)N(C)C(=O)CN5CCN(C)CC5)c5ccccc5)C(=O)Nc4c3)C(=O)CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1. References: Xue C, et al. Efficacy of BIBF 1120 or BIBF 1120 plus chemotherapy on nasopharyngeal carcinoma in vitro and in vivo. Drug Des Devel Ther. 2016 Mar 15,10:1173-80.

Schlagworte:	BIBF 1120, Intedanib
Hersteller:	TargetMol
Hersteller-Nr:	T1777

Eigenschaften

Anwendung:	Targets FMS-like tyrosine kinase 1 [EC:2.7.10.1] (FLT1, VEGFR1)
MW:	539.62 D
Formel:	C31H33N5O4

Datenbank Information

CAS :	656247-17-5\| Passende Produkte
KEGG ID :	K04362 \| Passende Produkte

Handhabung & Sicherheit

Lagerung:	+4°C
Versand:	+4°C (International: +4°C)
Signalwort:	Danger
GHS-Piktogramme:
H-Sätze:	H301, H315, H318, H361, H372
P-Sätze:	P201, P202, P260, P264, P270, P280, P314, P321, P330, P301+P310, P302+P352, P305+P351+P338, P308+P313, P332+P313, P362+P364, P405, P501