Niflumic Acid

Niflumic acid is a selective inhibitor of COX-2. The IC50 values are 16 and 0.1 µM for human recombinant COX-1 and -2, respectively. The Ki values are 2 and 0.02 µM for ovine COX-1 and -2, respectively.Formal Name: 2-[[3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid. CAS Number: 4394-00-7. Synonyms: Donalgin, Nifluril, UP83. Molecular Formula: C13H9F3N2O2. Formula Weight: 282.2. Purity: >99%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 65 mg/ml, DMSO: 44 mg/ml, Ethanol: 39 mg/ml, PBS (pH 7.2): 600 µg/ml. lambdamax: 289, 340 nm. SMILES: OC(=O)c1cccnc1Nc1cccc(c1)C(F)(F)F. InChi Code: InChI=1S/C13H9F3N2O2/c14-13(15,16)8-3-1-4-9(7-8)18-11-10(12(19)20)5-2-6-17-11/h1-7H,(H,17,18)(H,19,20). InChi Key: JZFPYUNJRRFVQU-UHFFFAOYSA-N.