Nebularine

Description: Nebularine (9-(beta-D-Ribofuranosyl)-9H-purine) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting inert lymphoid malignancies and inducing apoptosis.The anticancer mechanism of Nebularine is dependent on the inhibition of DNA synthesis. Target: Apoptosis. Smiles: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2cncnc12. References: Rahman MS, et al. Nebularine (9-2'-deoxy-beta-D-ribofuranosylpurine) has the template characteristics of adenine in vivo and in vitro. Mutat Res. 1997 Jul 3,377(2):263-8.