Naftifine (hydrochloride)

Naftifine is an allylamine compound that blocks ergosterol biosynthesis in fungi by inhibiting squalene epoxidase (Ki = 1.1 µM for C. albicans epoxidase).Formal Name: N-methyl-N-[(2E)-3-phenyl-2-propen-1-yl]-1-naphthalenemethanamine, monohydrochloride. CAS Number: 65473-14-5. Synonyms: AW 105-843. Molecular Formula: C21H21N . HCl. Formula Weight: 323.9. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml, DMSO: 5 mg/ml, Ethanol: 5 mg/ml. lambdamax: 222, 255, 282 nm. SMILES: CN(C/C=C/C1=CC=CC=C1)CC2=C(C=CC=C3)C3=CC=C2.Cl. InChi Code: InChI=1S/C21H21N.ClH/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20,/h2-15H,16-17H2,1H3,1H/b11-8+,. InChi Key: OLUNPKFOFGZHRT-YGCVIUNWSA-N.