N-Hydroxysulfosuccinimide (sodium salt)

N-Hydroxysulfosuccinimide (sulfo-NHS) is a modifying reagent that, in the presence of a cross-linking reagent like carbodiimide or EDAC, converts carboxyl groups to amine-reactive sulfo-NHS esters. The cross-linker converts the carboxylic acid to an unstable o-acylisourea intermediate, which then reacts with the primary amine of sulfo-NHS to produce the stable product.Formal Name: 1-hydroxy-2,5-dioxo-3-pyrrolidinesulfonic acid, monosodium salt. CAS Number: 106627-54-7. Synonyms: Sulfo-NHS. Molecular Formula: C4H4NO6S . Na. Formula Weight: 217.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. lambdamax: 210 nm. SMILES: ON1C(CC(S([O-])(=O)=O)C1=O)=O.[Na+]. InChi Code: InChI=1S/C4H5NO6S.Na/c6-3-1-2(12(9,10)11)4(7)5(3)8,/h2,8H,1H2,(H,9,10,11),/q,+1/p-1. InChi Key: RPENMORRBUTCPR-UHFFFAOYSA-M.