N-didesmethyl Loperamide

Artikelnummer	Größe	Datenblatt	Manual	SDB	Lieferzeit	Menge	Preis
Cay39559-1	1 mg		-		6 - 10 Werktage*		240,00 €
Cay39559-5	5 mg		-		6 - 10 Werktage*		419,00 €

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N-didesmethyl Loperamide is an active metabolite of the peripheral µ1-opioid receptor agonist... mehr

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Produktinformationen "N-didesmethyl Loperamide"

N-didesmethyl Loperamide is an active metabolite of the peripheral µ1-opioid receptor agonist loperamide. It inhibits electricity-induced contractions in isolated guinea pig myenteric plexus (IC50 = 370 nM). N-didesmethyl Loperamide sensitizes a chloroquine-resistant P. falciparum strain to chloroquine (EC50 = 482 nM) without inducing toxicity in A-10 vascular smooth muscle cells (IC50 = >10,000 nM).Formal Name: 4-(4-chlorophenyl)-4-hydroxy-alpha,alpha-diphenyl-1-piperidinebutanamide. CAS Number: 66164-06-5. Synonyms: R 21345. Molecular Formula: C27H29ClN2O2. Formula Weight: 449.0. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: slightly soluble, Chloroform: sparingly soluble. SMILES: NC(C(C1=CC=CC=C1)(C2=CC=CC=C2)CCN3CCC(C4=CC=C(Cl)C=C4)(O)CC3)=O. InChi Code: InChI=1S/C27H29ClN2O2/c28-24-13-11-21(12-14-24)26(32)15-18-30(19-16-26)20-17-27(25(29)31,22-7-3-1-4-8-22)23-9-5-2-6-10-23/h1-14,32H,15-20H2,(H2,29,31). InChi Key: PXJHDOGGBLQFRX-UHFFFAOYSA-N.

Schlagworte:	R 21345, 4-(4-chlorophenyl)-4-hydroxy-alpha,alpha-diphenyl-1-piperidinebutanamide
Hersteller:	Cayman Chemical
Hersteller-Nr:	39559

Eigenschaften

Anwendung:	Active loperamide ametabolite
MW:	449 D
Formel:	C27H29ClN2O2
Reinheit:	>95%
Format:	Solid

Datenbank Information

CAS :	66164-06-5\| Passende Produkte
KEGG ID :	K04215 \| Passende Produkte

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	+20°C (International: -20°C)
Signalwort:	Danger
GHS-Piktogramme:
H-Sätze:	H301
P-Sätze:	P264, P270, P301+310, P321, P330, P405, P501