N-desmethyl Sildenafil

N-desmethyl Sildenafil is a major metabolite of sildenafil (Cay-10008671, Cay-14008). N-desmethyl Sildenafil is formed via oxidative metabolism of sildenafil by the cytochrome (CYP) P450 isoforms CYP3A4, CYP3A5, and CYP3A7.Formal Name: 5-[2-ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one. CAS Number: 139755-82-1. Synonyms: UK-103320. Molecular Formula: C21H28N6O4S. Formula Weight: 460.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMSO: 10 mg/ml, DMSO:PBS (pH 7.2)(1:5): 0.15 mg/ml. lambdamax: 212, 293 nm. SMILES: CCOC1=C(C2=NC(C(CCC)=NN3C)=C3C(N2)=O)C=C(C=C1)S(N4CCNCC4)(=O)=O. InChi Code: InChI=1S/C21H28N6O4S/c1-4-6-16-18-19(26(3)25-16)21(28)24-20(23-18)15-13-14(7-8-17(15)31-5-2)32(29,30)27-11-9-22-10-12-27/h7-8,13,22H,4-6,9-12H2,1-3H3,(H,23,24,28). InChi Key: UZTKBZXHEOVDRL-UHFFFAOYSA-N.