N-Acetyl-D-Glucosamine

Description: N-Acetyl-D-Glucosamine (NAG) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc. Target: Endogenous Metabolite. Smiles: [C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)(NC(C)=O)C=O. References: Liu F,etal.O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease.Proc Natl Acad Sci U S A. 2004 Jul 20,101(29):10804-9.