N-5-Carboxypentyl-1-deoxynojirimycin

Description: 1-Deoxynojirimycin, a potent glucose analog, inhibits alpha-glucosidase I and II effectively. Its derivative, N-5-Carboxypentyl-1-deoxynojirimycin, serves as a ligand for glucosidase I and II purification, utilizing carboxypentyl groups for affinity chromatography resin linkage. Furthermore, N-5-Carboxypentyl-1-deoxynojirimycin demonstrates comparable or superior inhibition of glucosidase compared to 1-deoxynojirimycin, with inhibition constants (Ki) of 0.45 µM and 2.1 µM, respectively, for pig liver glucosidase I. Target: Others. Smiles: OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCC(O)=O