Muristerone A

Potent member of the ecdysteroid family - Ecdysone receptor (EcR) agonist - Analog of ecdysone with similar properties to ponasterone A (Prod. No. AG-CN2-0053) - Inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals - Induces apoptosis in cells transfected with wild-type Bax - Induces expression of beta-galactosidase - Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells - Insect steroid hormone involved in regulating metamorphosis, causing a response to G2 cell cycle arrest - Major molting hormone in some insects. Has protective effects in plants.