MOTS-c

Description: MOTS-c is a mitochondria-derived polypeptide (MDP) that has anti-damage and anti-inflammatory effects by activating the AMPK pathway and inhibiting the MAP kinase-c-fos signaling pathway. Target: Others. Smiles: C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CC(C)C)=O)CCCCN)=O)CCCNC(=N)N)=O)CCC2)CC3=CC=C(O)C=C3)=O)CC4=CC=CC=C4)=O)[C@H](CC)C)=O)=O)=O)CCSC)=O)CCC(O)=O)=O)CCC(N)=O)=O)NC([C@@H](NC([C@H](CCSC)N)=O)CCCNC(=N)N)=O)C=5C=6C(NC5)=CC=CC6. References: Yin X, et al. Eur J Pharmacol. 2020 Mar 5,870:172909.