MLS-573151

Description: MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 µM). It is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42. Target: CDK, Ras. Smiles: NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccccc1)c1ccccc1. References: Fan Mao, et al. Transcriptomic Evidence Reveals the Molecular Basis for Functional Differentiation of Hemocytes in a Marine Invertebrate, Crassostrea gigas. Front Immunol. 2020 May 27,11:911.