ML-137

NEU

Artikelnummer	Größe	Manual	Lieferzeit	Preis
Cay40918-5	5 mg	-	6 - 10 Werktage*	34,00 €
Cay40918-10	10 mg	-	6 - 10 Werktage*	65,00 €
Cay40918-50	50 mg	-	6 - 10 Werktage*	252,00 €
Cay40918-100	100 mg	-	6 - 10 Werktage*	402,00 €

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ML-137 is a positive allosteric modulator (PAM) of M1 muscarinic acetylcholine receptors... mehr

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Produktinformationen "ML-137"

ML-137 is a positive allosteric modulator (PAM) of M1 muscarinic acetylcholine receptors (mAChRs). It is selective for M1 over M2-M5 mAChRs at 30 µM. ML-137 potentiates ACh-induced activation of the M1 muscarinic receptor (EC50 = 0.83 µM).Formal Name: 1-[[2-fluoro-4-(1-methyl-1H-pyrazol-4-yl)phenyl]methyl]-1H-indole-2,3-dione. CAS Number: 1222834-53-8. Synonyms: VU0366369. Molecular Formula: C19H14FN3O2. Formula Weight: 335.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Slightly Soluble: 0.1-1 mg/ml. SMILES: FC1=CC(C2=CN(C)N=C2)=CC=C1CN3C(C(C4=C3C=CC=C4)=O)=O. InChi Code: InChI=1S/C19H14FN3O2/c1-22-10-14(9-21-22)12-6-7-13(16(20)8-12)11-23-17-5-3-2-4-15(17)18(24)19(23)25/h2-10H,11H2,1H3. InChi Key: JCOKRGWZMBZKFO-UHFFFAOYSA-N.

Schlagworte:	VU0366369, 1-[[2-fluoro-4-(1-methyl-1H-pyrazol-4-yl)phenyl]methyl]-1H-indole-2,3-dione
Hersteller:	Cayman Chemical
Hersteller-Nr:	40918

Eigenschaften

Anwendung:	M1 muscarinic receptor PAM (positive allosteric modulator)
MW:	335.3 D
Formel:	C19H14FN3O2
Reinheit:	>98%
Format:	Solid

Datenbank Information

CAS :	1222834-53-8\| Passende Produkte
KEGG ID :	K04129 \| Passende Produkte

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	+20°C (International: -20°C)
Signalwort:	Warning
GHS-Piktogramme:
H-Sätze:	H302, H315, H319, H335
P-Sätze:	P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501