MitoPerOx

MitoPerOx is a ratiometric fluorescent probe that can be used to assess changes in lipid peroxidation within mitochondria. It is composed of a BODIPY fluorophore conjugated via a dienyl link to a triphenylphosphonium cation component that drives its accumulation in mitochondria. MitoPerOx displays an excitation maximum of 495 nm and exhibits a shift in emission maxima from 590 to 520 nm upon mitochondrial lipid peroxidation, enabling determination of ratiometric measurements of lipid peroxidation in live cells.Formal Name: (2-(3-(5,5-difluoro-7-((1E,3E)-4-phenylbuta-1,3-dien-1-yl)-5H-5lambda4,6lambda4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)propanamido)ethyl)triphenylphosphonium, monobromide. CAS Number: 1392820-50-6. Molecular Formula: C42H38BF2N3OP . Br. Formula Weight: 760.5. Purity: >90%. Emission: 520-590 nm. Excitation: 495 nm. Formulation: (Request formulation change), A solid. Solubility: DMSO: 25 mM. SMILES: [F-][B+3]1([N-]2C(CCC(NCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)=O)=CC=C2C=C(C=C6)[N]1=C6/C=C/C=C/C7=CC=CC=C7)[F-].[Br-]. InChi Code: InChI=1S/C42H37BF2N3OP.BrH/c44-43(45)47-35(18-14-13-17-34-15-5-1-6-16-34)25-27-37(47)33-38-28-26-36(48(38)43)29-30-42(49)46-31-32-50(39-19-7-2-8-20-39,40-21-9-3-10-22-40)41-23-11-4-12-24-41,/h1-28,33H,29-32H2,1H/b17-13+,18-14+,. InChi Key: UDTNTHFRCJAKLR-GPSHETCQSA-N.