Miltefosine

Description: Miltefosine (HePC) is the treatment of visceral and cutaneous leishmaniasis drug , and is proceeding clinical trials for this in several countries. Several medical agents produce some potency against visceral or cutaneous leishmaniasis, however a 2005 survey concluded that miltefosine is the only effective oral treatment for both forms of leishmaniasis. Target: HIV Protease, Akt, PKC. Smiles: O(P(OCC[N+](C)(C)C)(=O)[O-])CCCCCCCCCC CCCCCC. References: Uberall F, et al. Y Res, 1991, 51(3), 807-812.