Milnacipran hydrochloride

Description: Milnacipran hydrochloride (Savella) is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders. Milnacipran hydrochloride is an enantiomer of milnacipran, which is used to treat fibromyalgia. Milnacipran hydrochloride and milnacipran have been associated with a low rate of transient elevations in serum aminotransferase levels during treatment and with rare instances of clinically apparent acute liver injury with jaundice. Target: Norepinephrine, Serotonin Transporter. Smiles: Cl.C1[C@@H]([C@@]1(C(=O)N(CC)CC)c1ccccc1)CN. References: Chen C, et al. Bioorg Med Chem Lett, 2008, 18(4), 1346-1349.