Microcystin-RR

Microcystin-RR is a cyanotoxin and an inhibitor of protein phosphatase 1C (PP1C), PP1gamma, and PP2A (Kis = 0.15, 0.24, and 0.018 nM, respectively). Intratracheal administration of microcystin-RR (1,200 µg/kg) induces hepatic bleeding in mice. Microcystin-RR has been found in freshwater with cyanobacterial blooms.Formal Name: cyclo[2,3-didehydro-N-methylalanyl-D-alanyl-L-arginyl-(3S)-3-methyl-D-beta-aspartyl-L-arginyl-(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoyl-D-gamma-glutamyl]. CAS Number: 111755-37-4. Synonyms: Cyanoginosin-RR, MC-RR. Molecular Formula: C49H75N13O12. Formula Weight: 1038.2. Purity: >95%. Formulation: (Request formulation change), A clear film. Solubility: DMSO: soluble, Ethanol:Water: Soluble, Methanol: Soluble. SMILES: CC(/C=C/[C@H](NC([C@H](CCCNC(N)=N)NC([C@@H](C)[C@H](C(O)=O)NC([C@H](CCCNC(N)=N)NC1=O)=O)=O)=O)[C@H](C)C(N[C@@H](C(O)=O)CCC(N(C)C(C(N[C@@H]1C)=O)=C)=O)=O)=C\[C@@H]([C@H](CC2=CC=CC=C2)OC)C. InChi Code: InChI=1S/C49H75N13O12/c1-26(24-27(2)37(74-8)25-32-14-10-9-11-15-32)18-19-33-28(3)40(64)60-36(46(70)71)20-21-38(63)62(7)31(6)43(67)56-30(5)42(66)59-35(17-13-23-55-49(52)53)45(69)61-39(47(72)73)29(4)41(65)58-34(44(68)57-33)16-12-22-54-48(50)51/h9-11,14. InChi Key: NSQDNLWVBVLGHE-SINYXRRLSA-N.