Miconazole-d5

Miconazole-d5 is intended for use as an internal standard for the quantification of miconazole (Cay-15420) by GC- or LC-MS. Miconazole is an imidazole antifungal. It is active against C. parapsilosis, C. pseudotropicalis, C. albicans, C. neoformans, C. tropicalis, and C. guilliermondii (MICs = Trichophyton species, A. fumigatus, A. niger, B. brasiliensis, and B. dermatitidis. Miconazole (160 mg/kg) prevents infection with T. mentagrophytes and M. canis in mice. It also reduces lesion size in a guinea pig model of C. albicans infection. Formulations containing miconazole have been used in the treatment of various fungal infections.Formal Name: 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy-d2]ethyl-d3]-1H-imidazole. CAS Number: 1216653-50-7. Molecular Formula: C18H9Cl4D5N2O. Formula Weight: 421.2. Purity: >99% deuterated forms (d1-d5). Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: soluble, DMSO: Soluble, Methanol: Soluble. SMILES: ClC1=CC=C(C([2H])([2H])OC([2H])(C2=CC=C(Cl)C=C2Cl)C([2H])(N3C=CN=C3)[2H])C(Cl)=C1. InChi Code: InChI=1S/C18H14Cl4N2O/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22/h1-8,11,18H,9-10H2/i9D2,10D2,18D. InChi Key: BYBLEWFAAKGYCD-XJMIFHCFSA-N.